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Gut Supplements


  • Lumbrokinase Supplement

    Heart & Vessels
    Gut Health

    From

    $19.95

  • Irish Sea Moss Supplement

    Antioxidants
    Gut Health
    Immune Health

    From

    $19.95

  • S-Acetyl L-Glutathione Supplement

    Antioxidants
    Gut Health
    Liver Health

    From

    $32.95

  • Turkey Tail Mushroom Supplement

    Immune Health
    Antioxidants
    Gut Health

    From

    $19.95

  • Magnesium Citrate Supplement

    Heart & Vessels
    Gut Health
    Sleep

    From

    $19.95

  • Liposomal Glutathione Supplement

    Gut Health
    Antioxidants
    Liver Health

    From

    $29.95

  • Lactoferrin Supplement

    Gut Health
    Antioxidants

    From

    $26.95

  • Monolaurin Supplement

    Immune Health
    Gut Health

    From

    $19.95

  • Digestive Enzymes Supplement

    Gut Health

    From

    $19.95

  • Sulforaphane Supplement

    Heart & Vessels
    Gut Health

    From

    $19.95

  • Mimosa Pudica Seed Supplement

    Immune Health
    Gut Health

    From

    $22.95

  • Ox Bile Salt Supplement

    Immune Health
    Gut Health

    From

    $19.95

  • Colostrum Supplement

    Immune Health
    Gut Health

    From

    $19.95

  • Liquid Chlorophyll Supplement

    Gut Health
    Hair Skin and Nails

    From

    $19.95

  • Akkermansia Supplement

    Gut Health

    From

    $24.95

  • Milk Thistle Drops

    Liver Health
    Gut Health

    From

    $19.95

  • L-Glutamine Powder

    Active Lifestyle & Fitness
    Gut Health

    $24.95

  • L-Glutamine Supplement

    Active Lifestyle & Fitness
    Immune Health
    Gut Health

    From

    $14.95

  • GLP-1 Supplement

    Metabolism
    Heart & Vascular
    Gut Health

    From

    $19.95

  • Sold out

    Psyllium Husk Supplement

    Gut Health

    From

    $19.95

Overview

Gut health influences far more than digestion — it is directly connected to immune function, mood, skin health, hormonal balance, and nutrient absorption. Double Wood's gut health collection addresses the full spectrum of digestive wellness: from microbiome support and mucosal integrity to enzyme production, motility, and pathogen clearance. Single-ingredient products let you identify what your gut specifically needs rather than relying on generalized blends.

What To Look For

The gut health category covers several distinct mechanisms. Digestive Enzymes support macronutrient breakdown and nutrient absorption, particularly useful for individuals with low stomach acid or pancreatic enzyme insufficiency. Berberine has significant evidence for supporting gut microbiome balance and reducing pathogenic overgrowth. L-Glutamine is the primary fuel source for enterocytes (intestinal lining cells) and supports gut barrier integrity. Colostrum provides immunoglobulins and growth factors that reinforce mucosal immunity. Magnesium Citrate supports motility. Lumbrokinase and Ox Bile Salt support digestive enzyme function and bile production. Akkermansia is a next-generation probiotic strain linked to improved gut barrier function and metabolic health. Mimosa Pudica Seed provides a unique mechanical cleansing action in the gut.

Frequently Asked Questions

What supplements are best for gut health and digestion?
The right supplement depends on the specific concern. For general digestive support, Digestive Enzymes and L-Glutamine (for gut lining integrity) are strong starting points. For microbiome support, Berberine has an unusually robust evidence base for its effects on gut flora, and Akkermansia targets the mucosal layer specifically. Magnesium Citrate supports healthy motility. Colostrum provides broad mucosal immune support. These can all be paired selectively based on your primary concern.
What does Berberine do for gut health?
Berberine has antimicrobial, anti-inflammatory, and microbiome-modulating effects in the gut. It inhibits the growth of pathogenic bacteria and certain parasitic organisms while supporting the production of short-chain fatty acids from beneficial bacteria. It is also one of the most studied natural options for blood sugar and lipid support, making it a multi-system supplement for metabolically active individuals.
What is Akkermansia and why is it different from standard probiotics?
Akkermansia muciniphila is a gut bacterium that lives in the intestinal mucus layer. Unlike standard probiotics that colonize the gut lumen, Akkermansia specifically supports the thickness and integrity of the mucosal barrier. Low Akkermansia levels are associated with metabolic dysfunction and increased intestinal permeability. It is considered a next-generation probiotic with a different mechanism from Lactobacillus and Bifidobacterium species.
- All Double Wood supplements are single-ingredient, third-party tested for purity and potency, and manufactured in cGMP-certified U.S. facilities. Certificates of Analysis are available for every product.