Gut Supplements

Lumbrokinase Supplement
Heart & Vessels
Gut Health

From
$19.95
Irish Sea Moss Supplement
Antioxidants
Gut Health
Immune Health

From
$19.95
S-Acetyl L-Glutathione Supplement
Antioxidants
Gut Health
Liver Health

From
$32.95
Turkey Tail Mushroom Supplement
Immune Health
Antioxidants
Gut Health

From
$19.95
Magnesium Citrate Supplement
Heart & Vessels
Gut Health
Sleep

From
$19.95
Liposomal Glutathione Supplement
Gut Health
Antioxidants
Liver Health

From
$29.95
Lactoferrin Supplement
Gut Health
Antioxidants

From
$26.95
Monolaurin Supplement
Immune Health
Gut Health

From
$19.95
Digestive Enzymes Supplement
Gut Health

From
$19.95
Sulforaphane Supplement
Heart & Vessels
Gut Health

From
$19.95
Mimosa Pudica Seed Supplement
Immune Health
Gut Health

From
$22.95
Ox Bile Salt Supplement
Immune Health
Gut Health

From
$19.95
Colostrum Supplement
Immune Health
Gut Health

From
$19.95
Liquid Chlorophyll Supplement
Gut Health
Hair Skin and Nails

From
$19.95
Akkermansia Supplement
Gut Health

From
$24.95
Milk Thistle Drops
Liver Health
Gut Health

From
$19.95
L-Glutamine Powder
Active Lifestyle & Fitness
Gut Health

$24.95
L-Glutamine Supplement
Active Lifestyle & Fitness
Immune Health
Gut Health

From
$14.95
GLP-1 Supplement
Metabolism
Heart & Vascular
Gut Health

From
$19.95
Sold out

Psyllium Husk Supplement
Gut Health

From
$19.95

Overview

Gut health influences far more than digestion — it is directly connected to immune function, mood, skin health, hormonal balance, and nutrient absorption. Double Wood's gut health collection addresses the full spectrum of digestive wellness: from microbiome support and mucosal integrity to enzyme production, motility, and pathogen clearance. Single-ingredient products let you identify what your gut specifically needs rather than relying on generalized blends.

What To Look For

The gut health category covers several distinct mechanisms. Digestive Enzymes support macronutrient breakdown and nutrient absorption, particularly useful for individuals with low stomach acid or pancreatic enzyme insufficiency. Berberine has significant evidence for supporting gut microbiome balance and reducing pathogenic overgrowth. L-Glutamine is the primary fuel source for enterocytes (intestinal lining cells) and supports gut barrier integrity. Colostrum provides immunoglobulins and growth factors that reinforce mucosal immunity. Magnesium Citrate supports motility. Lumbrokinase and Ox Bile Salt support digestive enzyme function and bile production. Akkermansia is a next-generation probiotic strain linked to improved gut barrier function and metabolic health. Mimosa Pudica Seed provides a unique mechanical cleansing action in the gut.

Frequently Asked Questions

What supplements are best for gut health and digestion?

The right supplement depends on the specific concern. For general digestive support, Digestive Enzymes and L-Glutamine (for gut lining integrity) are strong starting points. For microbiome support, Berberine has an unusually robust evidence base for its effects on gut flora, and Akkermansia targets the mucosal layer specifically. Magnesium Citrate supports healthy motility. Colostrum provides broad mucosal immune support. These can all be paired selectively based on your primary concern.

What does Berberine do for gut health?

Berberine has antimicrobial, anti-inflammatory, and microbiome-modulating effects in the gut. It inhibits the growth of pathogenic bacteria and certain parasitic organisms while supporting the production of short-chain fatty acids from beneficial bacteria. It is also one of the most studied natural options for blood sugar and lipid support, making it a multi-system supplement for metabolically active individuals.

What is Akkermansia and why is it different from standard probiotics?

Akkermansia muciniphila is a gut bacterium that lives in the intestinal mucus layer. Unlike standard probiotics that colonize the gut lumen, Akkermansia specifically supports the thickness and integrity of the mucosal barrier. Low Akkermansia levels are associated with metabolic dysfunction and increased intestinal permeability. It is considered a next-generation probiotic with a different mechanism from Lactobacillus and Bifidobacterium species.

- All Double Wood supplements are single-ingredient, third-party tested for purity and potency, and manufactured in cGMP-certified U.S. facilities. Certificates of Analysis are available for every product.