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Spermidine Supplement

$39.95

Spermidine is a natural compound that supports cellular health and metabolism, found in foods like peppers and mushrooms.

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Description

Spermidine is a polyamine molecule essential to cellular metabolism, present in foods like wheat germ, soybeans, aged cheese, and mushrooms — but only in trace amounts. To reach the doses studied in human aging research (typically 1.2–6mg per day), most people need a supplement.


Double Wood's Spermidine is a single-compound formula: 99% pure spermidine trihydrochloride (3HCL), the water-soluble salt form used in clinical research. Each two-capsule serving delivers 10mg of verified spermidine — independently tested by HPLC every batch, with full results published on this page. No wheat germ extract, no fillers, no batch-to-batch potency drift.


Soy-Free, Gluten-Free, Non-GMO, Vegan

Benefits

  • VERIFIED 99% SPERMIDINE 3HCL: A single-compound formula, HPLC-tested every batch and disclosed publicly to the milligram. 10mg spermidine per serving — no fillers, no extract variability.
  • TRANSPARENT BATCH TESTING: Every lot is tested by AILAB for purity, heavy metals, and microbials. Results published in full on this page — not buried in a downloadable PDF.
  • ALLERGEN-FREE LONGEVITY SUPPORT: Vegan, gluten-free, soy-free, non-GMO. Wheat-germ-derived spermidine supplements can trigger gluten and wheat sensitivities — our 3HCL form contains neither.
  • TELOMERE SUPPORT SUPPLEMENT: Spermidine plays a crucial role in the process of cell renewal and may help preserve telomere length as you age
  • WE BOTTLE WELLNESS: At Double Wood, we provide pure, potent supplements that deliver exceptional value, all backed by careful sourcing and rigorous third-party testing

Directions & Dosage

We recommend starting with a 1-2 capsule dosage of 5-10 mg, which can be increased to a 2-4 capsule dosage of 10 – 20 mg if desired. We don’t recommend exceeding a 4 capsule dosage. This product can be taken with or without food.

Identity, potency, and contaminants verified per batch Identity, potency, and contaminants verified per batch
Manufactured in an FDA-registered cGMP facility Manufactured in an FDA-registered cGMP facility
Manufactured in the USA from Gloabally Sourced Materials Manufactured in the USA from Gloabally Sourced Materials

Benefits

  • Supports Healthy Aging: Spermidine supports healthy aging and longevity due to its role in the process of cell renewal.
  • Supports Healthy Cognition: Spermidine can help support healthy memory and cognitive function.
Benefits

Spermidine

A polyamine naturally present in wheat germ and soy. It is recognized in traditional wellness practices and modern nutrition. It is commonly chosen to supports cellular renewal processes (autophagy) and healthy aging.

Spermidine

What Customers Are Saying

Reviews

"Reputation of product and overall delivery and ordering experience has always been a good experience."

Jacqueline P.

"Always fast shipping and great selection no matter what you’re looking for."

Aaron B.

"Double Wood is always my go-to for supplements. Great, effective, clean products and always at a reasonable price."

Jan W.

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Reviews
Supplement Facts

Pairs well with

Powerful alone, stronger together. Spermidine Supplement delivers targeted support on its own, but combining it with complementary ingredients can help create a more holistic and balanced approach to wellness.

Frequently Asked Questions

What does spermidine do?

Spermidine is a naturally occurring polyamine that promotes autophagy—a cellular recycling process that removes damaged components and supports overall cell health. This activity has been linked to potential benefits in longevity, cardiovascular function, and cognitive health.

What is spermidine good for?

Spermidine is known for promoting autophagy—a natural cellular recycling process that helps maintain cell health by clearing out damaged components. This effect may contribute to benefits in healthy aging, cardiovascular function, and cognitive performance,

How much spermidine per day?

Spermidine supplementation typically ranges from about 1 to 3 mg per day, though exact dosages may vary depending on the product and individual needs

Best time to take spermidine?

The best time to take spermidine isn't firmly established, but many users prefer taking it with a meal—often in the morning or at lunchtime—to support daily cellular renewal processes. This timing may help optimize absorption and ensure that your cells benefit from its autophagy-promoting effects throughout the day.

Where does spermidine come from?

Spermidine is a naturally occurring polyamine found in nearly all living cells. It is abundant in various foods, including aged cheese, soy products, legumes, and whole grains, and is also synthesized by our bodies as part of normal metabolic processes.

Overall rating: 4.6923075 / 5 from 26 reviews.

AI Generated Review Summary

Summary topics

Review topics: ["skin","results","quality"].

Review highlights

Reviews

Spermidine

"Don’t know how to rate this product as it is associated with longevity and I have been on it a relatively short amount of time. Tell me what I should look for and I will be glad to monitor myself. Picked your version even though the generally suggested dose of 13 mg per day takes 3 capsules to achieve because of the presumed quality of the other products that I purchase from you."

Alan O. (5/5)

New User

"I have used Spermidine for approximately 1 month. I do not have any side effects so far. I have no idea if I am receiving any benefits to my health."

Gary R. (1/5)

Spermidine capsules

"Since DoubleWoods Spermidine is NOT derived from wheat germ, it is gluten free! I experience a filing of wellbeing and found research that spermidine lowers inflammation in the gut."

William G. (5/5)

I love this supplement

"I have been taking this for over 12 months now and I have felt a difference in myself. It is the one supplement I never like to miss. I noticed a difference within the first week. More energy and more alive. I definitely recommend it."

Danielle K. (5/5)

"Arrived in time"

Ashish (5/5)

Spermidine

"This recommended as a nutropic. I also do breath work and intensive workouts so hard to tell affects. Seems like a quality sipplement."

Letitia N. (5/5)

Fantastic

"This is THE best Spermidine on the market hands down. I have noticed: Better Sleep, younger skin, regeneration in injuries and less inflammation overall. This supplement makes me younger. I have used Do NOT AGe spermidine along with a few other brands. I compared the results using Doublewoods Spermidine to the others and I must say that Doublewood's spermidine surpasses the others. My skin looks 10 years younger from this supplement. I also take Doublewood Pterostilbeine (2 caps a day and astxanthin 3-6 caps a day. I use Do Not age Sirt 6 activator (2 caps) and their Fisetin 2 caps a day with fatty meal. I also use Renue By Science NMN which is the brand Dr. Huberman uses. All of the listed supplements were from my research of Dr. David Sinclair's anti-aging protocal. All of these supplements make a difference. Pterostilbeine from doublewood got rid of eye floaters for me and the astaxanthin helped those as well as made my skin tan better and prevents sun damage. The spermidine is by far my favorite supplement because my skin looks so much younger. I am almost 46 and my neices who are on their teens and 20s seem to thinkk I look like I am 28. While I think that may be a stretch, I will say this Spermidine is to thank for a large portion of my skin looking young :)"

Dawn (5/5)

Every morning w my NMN

"This along w NMN,TMG,Apgenine,Ca/AKG,Psterobinine, Multi vitamin, Choline, Uridine,NMNH,Quecertin, CoQ10,will give you everything daily for your longevity needs. Important thing is you gotta stay with it. After 6 months you'll see vast improvement w High BP,kidney adrenal function. Cardiovascular, and lastly,improved energy and skin. U can't go wrong for all the men out their struggling over 50."

Christopher M. (5/5)

Believer!!!

"Love this product."

Shannon N. (5/5)

Spermidine

"I am healthy and happy with 2 pills of Spermidine daily. I drink since 2020 9ph Kangen water to keep my body alkaline"

Anna E. (5/5)

Q&A

Spermidine Supplement

From

$39.95

Primary Benefit

Healthy Aging

Other Benefits

Brain Health, Hair Skin and Nails

Product Form

Capsule
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